Generic Viagra: Standing Strong With Viagra
By Suzanne Ann

Viagra was discovered by chance. The medicinal compound sildenafil citrate was initially developed to treat patients who had heart problems. During these early clinical trials, an unexpected 'side effect' was discovered - that the medicine could improve and maintain a man's erection. Clinical trials of this effect were started in healthy male volunteers and then in patients with male erectile dysfunction. And in 1998 Viagra was approved by FDA as the first oral pill to treat Erectile Dysfunction.

Viagra caught on like fire as it was answer to millions of men who were suffering from Erectile Dysfunction. It was called the ‘blue magic pill’. After the success of Viagra many drug manufacturers launched the generic version of Viagra as Generic Viagra as Pfizer holds patent for Viagra. Some of the variants of Generic Viagra are Kamagra, Penegra, Cavetra and Siligra.

The price was the tumbling block for Pfizer which markets Viagra. Generic Viagra is available at half the cost of the branded Viagra. A few years ago Pfizer had launched a public awareness ad campaign against the sellers of “Generic Viagra” to help educate consumers about how to avoid illegitimate websites, safely purchase genuine Viagra online and help minimize selling of cheap Generic Viagra.

One can buy Generic Viagra online as they are easily available on internet pharmacies. One can check out from one of many online generic Viagra pharmacies

Chemical for keeping human pluripotent stem cells alive identified
Researchers have found that a chemically synthesized compound, blebbistatin, can help prevent cell death in human pluripotent stem cells. These cells are of interest to stem cell scientists working on finding therapies for spinal cord injuries, Parkinson's disease, burns, heart disease, diabetes, arthritis, and other ailments. Another advantage of using blebbistatin, say the researchers, is that no human- or animal-derived materials is needed for coating the culture surfaces. (Source: ScienceDaily Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Regular statin use is associated with a reduced risk of developing rheumatoid arthritis
There is an association between taking statins (lipid lowering drugs), and reduced risk of developing the chronic inflammatory disease, rheumatoid arthritis. (Source: ScienceDaily Headlines)
P2.51 The increased expression of B cell activating factor (BAFF) in patients with dermatomyositis
This study was aimed to investigate the role of BAFF in the immunopathogenesis of DM. (Source: Neuromuscular Disorders)
Patients on statins to lower cholesterol 'at less risk of arthritis' study finds
Drugs taken by millions of patients to cut cholesterol levels may also keep arthritis at bay. (Source: the Mail online | Health)
Risedronic acid: First report of acute arthritis: case report
(Source: Reactions)
Statins 'may cut arthritis risk'
Taking statins may reduce the risk of developing rheumatoid arthritis, a study suggests. (Source: BBC News | Health | UK Edition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
J&J Seeks Remicade Damages
Johnson & Johnson is seeking damages from Merck as it negotiates to dissolve a partnership over the big-selling rheumatoid arthritis drug Remicade. (Source: WSJ.com: Health)
What Causes Peripheral Neuropathy?
Discussion Peripheral neuropathy is simply a disease of the peripheral nerves. They can be acute (30%) or chronic (about 67%). About 70% of chronic neuropathy in children is hereditary, 20% is indeterminant and 10% is acquired. Peripheral neuropathies are often present with predominantly distal involvement that is bilateral and symmetric. Sensory symptoms can include numbness, dysesthesia or ataxia. Motor symptoms often include weakness. The autonomic nervous system can also be affected with arrhythmias, hypotension, bowel or bladder problems or abnormal sweating. Learning Point The differential diagnosis of peripheral neuropathy includes: Neurologic Abetaliporteinemia Charcot-Marie Tooth Disease Chronic Inflammatory Demyelinating Polyneuropathy Dejerine-Sottas Giant Axonal Neuropathy Gu...
Long-term weight loss may be harmful to health
HONG KONG (Reuters) - Long-term weight loss may release into the blood industrial pollutants linked to illnesses like diabetes, hypertension and rheumatoid arthritis, researchers said on Tuesday. (Source: Reuters: Health)
Casing the joint
(American Journal of Pathology) Current research provides a novel model for rheumatoid arthritis research. The related report by LaBranche et al., "Characterization of the KRN cell transfer model of rheumatoid arthritis (KRN-CTM), a chronic yet synchronized version of the K/BxN mouse," appears in the September 2010 issue of the American Journal of Pathology. (Source: EurekAlert! - Medicine and Health)
Researchers at UC Riverside find solution to cell death problem vexing stem cell research
(University of California - Riverside) Researchers at the University of California, Riverside, have found that a chemically synthesized compound, blebbistatin, can help prevent cell death in human pluripotent stem cells. These cells are of interest to stem cell scientists working on finding therapies for spinal cord injuries, Parkinson's disease, burns, heart disease, diabetes, arthritis, and other ailments. Another advantage of using blebbistatin, say the researchers, is that no human- or animal-derived materials is needed for coating the culture surfaces. (Source: EurekAlert! - Medicine and Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
NIH expands network focused on how genes affect drug responses
(NIH/National Institute of General Medical Sciences) NIH plans to spend $161.3 million over the next five years to expand the nationwide Pharmacogenomics Research Network. Since its launch in 2000, the network has studied how genes affect individual responses to medicines for heart disease, asthma, various cancers, nicotine addiction and other conditions. In addition to these areas, the expanded network will focus on rheumatoid arthritis, bipolar disorder and the use of pharmacogenetics in rural and underserved populations. (Source: EurekAlert! - Medicine and Health)
The effect of infliximab plus methotrexate on the modulation of inflammatory disease markers in juvenile idiopathic arthritis: analyses from a randomized, placebo-controlled trial
Conclusion: Infliximab + MTX attenuated several inflammatory markers in patients with JIA; larger decreases in ICAM-1, MMP-3, and CRP levels were observed in ACR-Pedi-30 responders versus nonresponders.Trial Registration: NCT00036374 (Source: BioMed Central)
Topical Gel Catches Up With Pills for Relief
Controlled trials suggest that a topical nonsteroidal anti-inflammatory drug in a cream is as effective as their oral counterparts for treating osteoarthritis, soreness and tendinitis. (Source: NYT Health)
Discovering a New Source of Wrist Pain
(Ivanhoe Newswire) -- Millions of people are diagnosed with carpal tunnel syndrome and arthritis every year. (Source: Medical Headlines From Ivanhoe.com)
RESEARCH: Effects of Long?Term Disease?Modifying Antirheumatic Drugs on Endothelial Function in Patients with Early Rheumatoid Arthritis
Rheumatoid arthritis (RA) is associated with enhanced atherosclerosis and impaired endothelial function early after the onset of the disease and cardiovascular (CV) disease represents one of the leading causes of morbidity and mortality. It is well known that disease modifying antirheumatic drugs (DMARDs) are able to improve the course of the disease and the quality of life of these patients, but little is known about the effects of DMARDs on CV risk and endothelial dysfunction. Our goal was to examine the effects of long?term therapy with DMARDs on endothelial function and disease activity in early RA (ERA). Twenty?five ERA patients (mean age 52 ± 14.6 years, disease duration 6.24 ± 4.10 months) without evidence of CV involvement were evaluated for disease activity score (DAS?28),...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Low IgG Poses Infection Risk With Rituximab (CME/CE)
(MedPage Today) -- Certain subgroups of patients with rheumatoid arthritis, particularly those who have low levels of IgG, are at risk for severe infections when treated with rituximab, French investigators found. (Source: MedPage Today Geriatrics)
Acupuncture Not Superior to Sham Acupuncture in Knee Osteoarthritis
Does acupuncture work for patients with knee osteoarthritis? Arthritis Care Research News Alerts (Source: Medscape Orthopaedics Headlines)
Beneficial Effect of Eucommia Polysaccharides on Systemic Lupus Erythematosus-like Syndrome Induced by Campylobacter jejuni in BALB/c Mice
This study was to determine whether the crude polysaccharides (EUPs) isolated from the stem bark of E. ulmoides had beneficial effects on lupus-like syndrome in mice. BALB/c mice were immunized with CJ-S131 in Freund?s complete adjuvant on day&nbsp;0, and then boosted on day&nbsp;14. EUPs 15 or 30&nbsp;mg?kg?1·day?1, or prednisone 5&nbsp;mg?kg?1·day?1 was given to BALB/c mice intragastrically from day&nbsp;0 to 34. Treatment with EUPs 15 or 30&nbsp;mg?kg?1·day?1 for 35&nbsp;days protected kidney from glomerular injury with reduced immunoglobulin deposition and lowered proteinuria. The increased production of serum autoantibodies and total immunoglobulin G (IgG) was also inhibited. These findings suggested that Eucommia polysaccharides had a beneficial effect on syst...
Fatty acids 'may prevent diabetes'
The secret of how fish oil helps prevent heart disease and diabetes is believed to have been unlocked by scientists who now hope to develop new dietary remedies and drugs to reduce conditions such as type-2 diabetes, heart disease and arthritis. (Source: Nursing Times Breaking News)
Genetic and therapeutic targeting of properdin in mice prevents complement-mediated tissue injury
The alternative pathway (AP) of complement activation is constitutively active and must be regulated by host proteins to prevent autologous tissue injury. Dysfunction of AP regulatory proteins has been linked to several human inflammatory disorders. Properdin is a positive regulator of AP complement activation that has been shown to extend the half-life of cell surface&#x02013;bound C3 convertase C3bBb; it may also initiate AP complement activation. Here, we demonstrate a critical role for properdin in autologous tissue injury mediated by AP complement activation. We identified myeloid lineage cells as the principal source of plasma properdin by generating mice with global and tissue-specific knockout of Cfp (which encodes properdin) and by generating BM chimeric mice. Properdin deficiency...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Ancient 'Paleo' diet key to healthy living and weight loss, some say
(NaturalNews) Eat like a cave man to lose weight, build muscle and feel great. This is what advocates of the "Paleo" diet say is the key to healthy living, a diet that consists only of meat, vegetables, fruits, nuts, seeds and mushrooms -- also known as the "Paleolithic", or Paleo diet.A recent Chicago Tribune article tells the story of Rick Larson, co-owner of a West Sacramento, Calif., gym called CrossFit. Larson, a Paleo diet supporter, explains in the story that many of his gym members were getting great workouts, but that few were following healthy diets. After experiencing incredible success himself on the Paleo diet, he decided to offer the program to his members as well."For the first time in my life, I started to feel quite healthy. I didn't get any respiratory problems, my arthri...
Osteoporosis Drugs May Be Linked to Cancer Risk
Title: Osteoporosis Drugs May Be Linked to Cancer RiskCategory: Health NewsCreated: 9/3/2010 8:58:00 AMLast Editorial Review: 9/3/2010 8:58:19 AM (Source: MedicineNet Arthritis General)
Loeys-Dietz Syndrome
Title: Loeys-Dietz SyndromeCategory: Diseases and ConditionsCreated: 9/7/2006Last Editorial Review: 9/3/2010 (Source: MedicineNet Arthritis General)
Hope for Arthritis Patients in Fat Tissue
A recent discovery at the UA College of Medicine ? that adult stem cells collected from fat tissue can be converted to cells that will grow cartilage tissue ? has focused one Arizona Arthritis Center lab&#39;s research, promising new hope for osteoarthritis sufferers. (Source: Health)
Hydrocortisone/methotrexate/prednisone: Septic arthritis in an elderly patient: case report
(Source: Reactions)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
The Big Egg Recall: Who is watching the U.S. hens?
Since May 2010, a higher than usual incidence of salmonellosis was reported in several parts of the US that covered 10 states. Salmonellosis is a potentially life-threatening foodborne illness caused by the bacterium Salmonella. Salmonella infection manifests as gastroenteritis, food poisoning or typhoid fever. Symptoms, which take up to 72 hours to appear, include vomiting, diarrhea, fever and abdominal cramps1. Even after recovering from salmonellosis, those infected may still suffer from recurring joint pain and reactive arthritis. (Source: Health WorldNet)
The Big Egg Recall: Who is Watching the Hens?
Since May 2010, a higher than usual incidence of salmonellosis was reported in several parts of the US that covered 10 states. Salmonellosis is a potentially life-threatening foodborne illness caused by the bacterium Salmonella. Salmonella infection manifests as gastroenteritis, food poisoning or typhoid fever. Symptoms, which take up to 72 hours to appear, include vomiting, diarrhea, fever and abdominal cramps.[1] Even after recovering from salmonellosis, those infected may still suffer from recurring joint pain and reactive arthritis. (Source: Health WorldNet)
What is the Evidence for Total Knee Arthroplasty in Young Patients?: A Systematic Review of the Literature.
CONCLUSIONS: TKA provides surgeon-measured clinical and functional improvements with a moderate increase in second-decade implant failures. Improvements in study design and reporting will be beneficial to guide decisions regarding implant selection and surgical technique. LEVEL OF EVIDENCE: Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence. PMID: 20814772 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Avesthagen gets 'process' patent for arthritis drug
Bangalore-based drugmaker Avesthagen has got the Indian patent for the process to make a biosimilar drug of Amgen's blockbuster medicine Enbrel. (Source: The Economic Times Healthcare and Biotech News)
Avesthagen gets 'process' patent for arthritis drug
Bangalore-based drugmaker Avesthagen has got the Indian patent for the process to make a biosimilar drug of Amgen's blockbuster medicine Enbrel. (Source: The Economic Times Healthcare and Biotech News)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Achieving Drug-free Remission: Elucidating the Role of TNF in Rheumatoid Arthritis
Read this study to learn about the increasing role of biologic therapies in the treatment of rheumatoid arthritis. International Journal of Clinical Rheumatology (Source: Medscape Rheumatology Headlines)
Efficacy and Safety of Various Repeat Treatment Dosing Regimens of Rituximab in Patients With Active Rheumatoid Arthritis: Results of a Phase III Randomized Study (MIRROR)
What is the most effective dosing method of rituximab in patients with active rheumatoid arthritis? Rheumatology (Source: Medscape Rheumatology Headlines)
Arthritis may block Alzheimer's
A protein produced in arthritis may ?protect against the development of Alzheimer's disease,? reported BBC News. US research on mice has discovered that a protein called GM-CSF, produced in rheumatoid arthritis, may trigger the immune system to destroy the protein plaques found in Alzheimer?s disease. (Source: Neurological Conditions Specialist Library)
Behind the headlines - arthritis may block Alzheimer's
A protein produced in arthritis may ?protect against the development of Alzheimer's disease,? reported BBC News. US research on mice has discovered that a protein called GM-CSF, produced in rheumatoid arthritis, may trigger the immune system to destroy the protein plaques found in Alzheimer?s disease. (Source: Neurological Conditions Specialist Library)
Long-term ocular complications in aphakic versus pseudophakic eyes of children with juvenile idiopathic arthritis-associated uveitis
Conclusion With maximum control of perioperative inflammation and intensive follow-up, the implantation of an intraocular lens in well-selected eyes of children with JIA-associated uveitis is not associated with an increased risk of ocular hypertension, secondary glaucoma, cystoid macular oedema and optic disc swelling and showed better visual results up to and including 7&nbsp;years after cataract extraction. (Source: British Journal of Ophthalmology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
DNA From National Psoriasis Victor Henschel BioBank Released For Study
Millions of Americans struggling with psoriasis and psoriatic arthritis are one step closer to a cure with the first-ever release of National Psoriasis Victor Henschel BioBank DNA samples for use in psoriasis research. The samples will allow scientists to uncover the unknowns about the genetics of psoriatic disease and its causes. James T. Elder, M.D., Ph.D... (Source: Health News from Medical News Today)
Original Article: Rheumatoid arthritis and birth outcomes: a Danish and Swedish nationwide prevalence study
Abstract.? (Source: Journal of Internal Medicine)
Editorial Comment: Rheumatoid arthritis and pregnancy: where do we go from here?
(Source: Journal of Internal Medicine)
Overactive Blood Platelets May Play Role in Lupus
Title: Overactive Blood Platelets May Play Role in LupusCategory: Health NewsCreated: 9/1/2010 4:10:00 PMLast Editorial Review: 9/2/2010 (Source: MedicineNet Arthritis General)
Case Study Reveals 'Percussionist Wrist' Injury
Title: Case Study Reveals 'Percussionist Wrist' InjuryCategory: Health NewsCreated: 9/1/2010 6:10:00 PMLast Editorial Review: 9/2/2010 (Source: MedicineNet Arthritis General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Ketoprofen pharmacokinetics, efficacy, and tolerability in pediatric patients.
In conclusion, ketoprofen is effective and well tolerated in children for the control of post-surgical pain and for the control of pain and fever in inflammatory conditions. PMID: 20799760 [PubMed - in process] (Source: Paediatric Drugs)
Predictors of interstitial lung disease in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohort
The objective was to examine the association of baseline demographic and clinical characteristics with sequentially obtained measurements of forced vital capacity (FVC, expressed as a percentage of the predicted value) and to identify predictors of decline rate in FVC over time in the Genetics versus Environment in Scleroderma Outcome Study (GENISOS). Methods: To date, 266 patients were enrolled in GENISOS, a prospective, observational cohort of patients with early systemic sclerosis. In addition to pulmonary function tests (PFT), clinical and laboratory data were obtained from each patient. We analyzed 926 FVC measurements utilizing generalized linear mixed models. The predictive significance of baseline variables for the decline rate in FVC was investigated by the interaction term betwee...
Impact of Prevalent Fractures on Quality of Life: Baseline Results From the Global Longitudinal Study of Osteoporosis in Women
CONCLUSION: Previous fractures at a variety of bone locations, particularly spine, hip, and upper leg, or involving more than 1 location are associated with significant reductions in quality of life. (Source: Mayo Clinic Proceedings)
Mainstream media now citing ridiculous junk science to discredit omega-3s
(NaturalNews) A study out of the Netherlands has put the mainstream media in a mindless tizzy about the health effects of omega-3 fatty acids. Because a group of people fed four teaspoons of omega-3-enriched margarine a day for more than three years did not experience a reduction in heart events, many media outlets are foolishly reporting that omega-3s are not as beneficial as commonly believed.Margarine, as many people now know, is a synthetic, hydrogenated food product that is actually not a food at all. It is a product composed of synthetic trans-fatty acids that are highly toxic and harmful to health. Margarine is exactly the type of substance that causes heart attacks and cardiovascular illness, making it ridiculous to include as part of a health study."[T]rans-fatty acids not only in...
Foot Pain
Title: Foot PainCategory: Diseases and ConditionsCreated: 5/13/2008Last Editorial Review: 9/1/2010 (Source: MedicineNet Arthritis General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Behind the headlines - Genetic effects of vitamin D studied
?Stocking up on vitamin D supplements and enjoying the summer sun could cut the risk of a host of diseases,? reported the Daily Mail. This news story is based on a study that investigated how vitamin D might influence the risk of certain diseases by affecting the activity of genes. It found that vitamin D binds directly to genes associated with several common autoimmune diseases, including multiple sclerosis, type 1 diabetes, rheumatoid arthritis and colorectal cancer. Studies of this kind add to our knowledge of the function of vitamin D, and will be used to assess the guidelines for recommended vitamin D intake. What does NHS Choices make of this study? This is a valuable addition to our knowledge of the effects of vitamin D in the cells and how it might affect our risk of certain di...
Behind the headlines - Genetic effects of vitamin D studied
?Stocking up on vitamin D supplements and enjoying the summer sun could cut the risk of a host of diseases,? reported the Daily Mail. This news story is based on a study that investigated how vitamin D might influence the risk of certain diseases by affecting the activity of genes. It found that vitamin D binds directly to genes associated with several common autoimmune diseases, including multiple sclerosis, type 1 diabetes, rheumatoid arthritis and colorectal cancer. Studies of this kind add to our knowledge of the function of vitamin D, and will be used to assess the guidelines for recommended vitamin D intake. What does NHS Choices make of this study? This is a valuable addition to our knowledge of the effects of vitamin D in the cells and how it might affect our risk of certain di...
Behind the headlines - Genetic effects of vitamin D studied
?Stocking up on vitamin D supplements and enjoying the summer sun could cut the risk of a host of diseases,? reported the Daily Mail. This news story is based on a study that investigated how vitamin D might influence the risk of certain diseases by affecting the activity of genes. It found that vitamin D binds directly to genes associated with several common autoimmune diseases, including multiple sclerosis, type 1 diabetes, rheumatoid arthritis and colorectal cancer. Studies of this kind add to our knowledge of the function of vitamin D, and will be used to assess the guidelines for recommended vitamin D intake. What does NHS Choices make of this study? This is a valuable addition to our knowledge of the effects of vitamin D in the cells and how it might affect our risk of certain di...
U-M researchers receive largest single collection of psoriasis DNA samples
(University of Michigan Health System) Millions of Americans struggling with psoriasis and psoriatic arthritis are one step closer to a cure with the release of the first National Psoriasis Victor Henschel BioBank DNA samples for use in research at the University of Michigan Health System; research that hopes to uncover the unknowns about the genetics of psoriasis and psoriatic arthritis. (Source: EurekAlert! - Medicine and Health)
Heterogeneity in juvenile idiopathic arthritis: Impact of molecular profiling based on DNA polymorphism and gene expression patterns
(Source: Arthritis and Rheumatism)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
?Muscles ? and bones?
(Source: Arthritis and Rheumatism)
Mast cells and type I interferon responses in the skin of patients with juvenile dermatomyositis: Are current therapies just scratching the surface?
(Source: Arthritis and Rheumatism)
Edward D. Harris, Jr., MD, 1937?2010
(Source: Arthritis and Rheumatism)
Risk factors for severe infections in patients with rheumatoid arthritis treated with rituximab in the autoimmunity and rituximab registry
Abstract (Source: Arthritis and Rheumatism)
Anti?apolipoprotein A?1 IgG predicts major cardiovascular events in patients with rheumatoid arthritis
Abstract (Source: Arthritis and Rheumatism)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Glucocorticoid?induced leucine zipper is an endogenous antiinflammatory mediator in arthritis
Abstract (Source: Arthritis and Rheumatism)
Increased friction coefficient and superficial zone protein expression in patients with advanced osteoarthritis
Abstract (Source: Arthritis and Rheumatism)
Involvement of different risk factors in clinically severe large joint osteoarthritis according to the presence of hand interphalangeal nodes
Abstract (Source: Arthritis and Rheumatism)
Human articular chondrocytes secrete parathyroid hormone?related protein and inhibit hypertrophy of mesenchymal stem cells in coculture during chondrogenesis
Abstract (Source: Arthritis and Rheumatism)
Hypoxia?inducible factor regulation of ANK expression in nucleus pulposus cells: Possible implications in controlling dystrophic mineralization in the intervertebral disc
Abstract (Source: Arthritis and Rheumatism)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Blockade of the interleukin?7 receptor inhibits collagen?induced arthritis and is associated with reduction of T cell activity and proinflammatory mediators
Abstract (Source: Arthritis and Rheumatism)
In vivo microfocal computed tomography and micro?magnetic resonance imaging evaluation of antiresorptive and antiinflammatory drugs as preventive treatments of osteoarthritis in the rat
Abstract (Source: Arthritis and Rheumatism)
Attenuation of osteoarthritis progression by reduction of discoidin domain receptor 2 in mice
Abstract (Source: Arthritis and Rheumatism)
A novel autoantibody recognizing 200?kd and 100?kd proteins is associated with an immune?mediated necrotizing myopathy
Abstract (Source: Arthritis and Rheumatism)
Racial disparities in age at time of cardiovascular events and cardiovascular?related death in patients with systemic lupus erythematosus
Abstract (Source: Arthritis and Rheumatism)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Interferon???dependent inhibition of B cell activation by bone marrow?derived mesenchymal stem cells in a murine model of systemic lupus erythematosus
Abstract (Source: Arthritis and Rheumatism)
Long?term remission after cessation of interferon?? treatment in patients with severe uveitis due to Behçet's disease
Abstract (Source: Arthritis and Rheumatism)
Lesional and nonlesional skin from patients with untreated juvenile dermatomyositis displays increased numbers of mast cells and mature plasmacytoid dendritic cells
Abstract (Source: Arthritis and Rheumatism)
Association of subclinical atherosclerosis and leukopenia in systemic autoimmune diseases: Comment on the article by Huang et al
(Source: Arthritis and Rheumatism)
Reply
(Source: Arthritis and Rheumatism)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Reply
(Source: Arthritis and Rheumatism)
Lymphoid aggregation is not lymphoid neogenesis: Comment on the article by Klaasen et al
(Source: Arthritis and Rheumatism)
Comparison between adalimumab, etanercept, and infliximab in rheumatoid arthritis: Comment on the article by Hetland et al
(Source: Arthritis and Rheumatism)
Reply
(Source: Arthritis and Rheumatism)
Imaging artifact explains apparent metacarpophalangeal joint erosions in healthy individuals: Comment on the article by Stach et al
(Source: Arthritis and Rheumatism)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Reply
(Source: Arthritis and Rheumatism)
Osteoarthritis, a basic calcium phosphate crystal?associated arthropathy? Comment on the article by Fuerst et al
(Source: Arthritis and Rheumatism)
National Psoriasis Foundation Discovery Research Grant
The National Psoriasis Foundation is seeking grant applications that encourage the advancement of innovative research in psoriasis and psoriatic arthritis. Discovery Research Grants are intended to allow researchers to undertake preliminary and proof of concept studies with the goal of developing competitive grant proposals that lead to long-term funding from the National Institutes of Health or other federal agencies. Research pathways: The National Psoriasis Foundation supports basic and clinical research that leads to the prevention, diagnosis and cure of psoriasis and psoriatic arthritis. Priority consideration will be given to applications that address one or more of the Foundation&rsquo;s research pathways: (1) genetics, (2) cell biology, (3) immunology, and (4) epidemiological...
National Psoriasis Foundation Translational Research Grant
The National Psoriasis Foundation is seeking grant applications that focus on the rapid translation of scientific discoveries arising from laboratory, clinical or population-based studies into clinical applications that have a clear benefit for patients with psoriasis and/or psoriatic arthritis. Research pathways: Priority consideration will be given to applications that address one or more of the Foundation&#39;s research pathways: (1) genetics, (2) cell biology, (3) immunology, and (4) epidemiological/health services research. Anticipated number of awards: It is anticipated that as many as four new Translational Research Grants will be awarded in 2011. Awards are contingent on the availability of funds and the receipt of sufficiently meritorious applications. Budget and Projec...
Increased muscle interstitial levels of inflammatory cytokines in polymyalgia rheumatica
(Source: Arthritis and Rheumatism)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Motion Deficit of the Thumb in CMC Joint Arthritis
Conclusions: Severe stages of thumb CMC OA cause an asymmetrical motion deficit with decreased ROM in extension and adduction, leading to decreased capability of counteropposition. (Source: The Journal of Hand Surgery)
ORIGINAL ARTICLE: Long?term study of infliximab in Japanese patients with plaque psoriasis, psoriatic arthritis, pustular psoriasis and psoriatic erythroderma
(Source: The Journal of Dermatology)
Ultrasound in American Rheumatology Practice: Report of the American College of Rheumatology Musculoskeletal Ultrasound Task Force
(Source: Arthritis Care and Research)
Varus?valgus laxity and passive stiffness in medial knee osteoarthritis
Abstract (Source: Arthritis Care and Research)
Thigh muscle strength, functional capacity, and self?reported function in patients at high risk of knee osteoarthritis compared with controls
Abstract (Source: Arthritis Care and Research)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Life strain?related tiredness and illness?related fatigue in individuals with ankylosing spondylitis
Abstract (Source: Arthritis Care and Research)
Serum uric acid and risk of occupational disability: Findings from a cohort study of male construction workers in Germany
Abstract (Source: Arthritis Care and Research)
Musculoskeletal pain and incident disability in community?dwelling older adults
Abstract (Source: Arthritis Care and Research)
Risk factors associated with renal lithiasis during uricosuric treatment of hyperuricemia in patients with Gout
Abstract (Source: Arthritis Care and Research)
Prevalence of cam?type deformity on hip magnetic resonance imaging in young males: A cross?sectional study
Abstract (Source: Arthritis Care and Research)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Rituximab therapy for myopathy associated with anti?signal recognition particle antibodies: A case series
Abstract (Source: Arthritis Care and Research)
Frequency and effectiveness of dose increase of adalimumab, etanercept, and infliximab in daily clinical practice
Abstract (Source: Arthritis Care and Research)
Cross?sectional comparison of extended anteroposterior and posteroanterior fixed flexion positioning to assess radiographic osteoarthritis at the knee: The Johnston County Osteoarthritis Project
Abstract (Source: Arthritis Care and Research)
A 39?year?old woman with Lupus, Myositis, and a Recalcitrant Vasculopathy
(Source: Arthritis Care and Research)
Does the intraclass correlation coefficient always reliably express reliability? Comment on the article by Cheung et al
(Source: Arthritis Care and Research)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Reply
(Source: Arthritis Care and Research)
ARHP announcements
(Source: Arthritis Care and Research)
T?cell expression of CD91 ? a marker of unresponsiveness to anti?TNF therapy in rheumatoid arthritis
(Source: APMIS)
Adherence, Discontinuation, and Switching of Biologic Therapies in Medicaid Enrollees with Rheumatoid Arthritis
ABSTRACT (Source: Value in Health)
A Case of Multicentric Castleman's Disease Having Lung Lesion Successfully Treated with Humanized Anti-interleukin-6 Receptor Antibody, Tocilizumab.
This report presents the case of a patient demonstrating multicentric Castleman's disease (MCD) with a lung lesion that was successfully treated with an anti-interleukin-6 receptor antibody, tocilizumab in combination with corticosteroid and tacrolimus. A 43-yr-old female with abnormal shadows on a chest X-ray was referred to the hospital for further examination. She was diagnosed as having MCD based on the characteristic pathology of inguinal lymph node, lung lesions, laboratory data, and undifferentiated arthritis. Corticosteroid and rituximab therapy did not fully ameliorate the symptoms; thus, the therapeutic regimen was changed to include tocilizumab, oral corticosteroid and tacrolimus. This regimen resulted in clinical remission and the dose of tocilizumab and corticosteroid could be...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Discontinuation of etanercept after successful treatment in patients with juvenile idiopathic arthritis.
Authors: Remesal A, DE Inocencio J, Merino R, Garcia-Consuegra J PMID: 20810527 [PubMed - in process] (Source: J Rheumatol)
Anticyclic citrullinated Peptide antibodies as markers of erosive arthritis in antisynthetase syndrome.
Authors: Cavagna L, Fusetti C, Montecucco C, Caporali R PMID: 20810525 [PubMed - in process] (Source: J Rheumatol)
Work-associated Arthritis Productivity Loss: Where Do We Stand in Its Measurement?
Authors: Burton WN, Schultz A, Chin CY, Edington DW PMID: 20810519 [PubMed - in process] (Source: J Rheumatol)
Early Predictors of Juvenile Sacroiliitis in Enthesitis-related Arthritis.
CONCLUSION: In our cohort, roughly 30% of children with ERA/juvenile idiopathic arthritis develop clinical and MRI evidence of sacroiliitis, detectable with dynamic MRI as early as 1 year after disease onset. Additional data from larger case series are needed to assess the specificity and sensitivity of this technique in the early phase of the disease and to confirm the rate of SI involvement reported in this cohort. PMID: 20810515 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Evaluation of Selected Rheumatoid Arthritis Activity Scores for Office-based Assessment.
CONCLUSION: In RA, the CDAI and RAPID correlated well with the DAS28-CRP4. They may both be practical and informative in the care of patients in the office setting. PMID: 20810513 [PubMed - as supplied by publisher] (Source: J Rheumatol)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Ultrasonographic Measurements of Joint Cartilage Thickness in Healthy Children: Age- and Sex-Related Standard Reference Values.
CONCLUSION: Using US, we established age- and sex-related normal reference intervals for cartilage thickness of the knee, ankle, wrist, and MCP and PIP joints in 7- to 16-year-old children, and designed a formula for calculating hyaline cartilage thickness in all age groups throughout childhood. PMID: 20810511 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Elevated Serum Glucose-6-Phosphate Isomerase Correlates with Histological Disease Activity and Clinical Improvement After Initiation of Therapy in Patients with Rheumatoid Arthritis.
CONCLUSION: Elevated serum GPI may be involved in the synovitis of RA and may prove useful as a serum marker for disease activity of RA. PMID: 20810510 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Pharmacologic Immunomodulation and Cutaneous Malignancy in Rheumatoid Arthritis, Psoriasis, and Psoriatic Arthritis (Review).
CONCLUSION: RA may potentiate the risk of cutaneous malignancy and therefore dermatologic screening in this population should be considered. The use of immunomodulatory therapy in RA, psoriasis, and PsA may further increase the risk of cutaneous malignancy and therefore dermatologic screening examinations are warranted in these groups. More careful recording of skin cancer development during clinical trials and cohort studies is necessary to further delineate the risks of immunomodulatory therapy. PMID: 20810498 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Psoriasis link
About 2% of the general population suffers from psoriasis, a chronic inflammatory disease that affects multiple systems but principally manifests in the skin and joints. Factors that modify this autoimmune disease include genetics, environment, trauma, drugs, sunlight, metabolic factors, psychogenic influences, alcohol, and smoking. Physical conditions associated with psoriasis are cardiovascular disease, metabolic syndrome, inflammatory bowel disease, rheumatoid arthritis, seronegative spondyloarthropathies, malignancy, streptococcal tonsillitis, smoking, alcohol abuse, psychiatric disorders, and stress. Additionally, streptococcal infections can precipitate psoriasis. In chronic destructive periodontal disease, the periodontal supporting tissues are destroyed in an immunologically motiva...
Type 1 diabetes associated with Hashimoto's thyroiditis and juvenile rheumatoid arthritis: a case report with clinical and genetic investigations
Nagy KH, Lukacs K, Sipos P, Hermann R, Madacsy L, Soltesz G. Type 1 diabetes associated with Hashimoto's thyroiditis and juvenile rheumatoid arthritis: a case report with clinical and genetic investigations. (Source: Pediatric Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
FGF?2 and PDGF, but not Platelet Lysate (PL), induce proliferation dependent, functional MHC?classII antigen in human mesenchymal stem cells (hMSC)
Abstract (Source: Arthritis and Rheumatism)
Atherosclerosis in systemic lupus : The role of antiphospholipid antibodies needs strict diagnostic criteria to be evaluated
(Source: Arthritis Care and Research)
Certain Exercises Benefit Arthritic Dogs
Walking uphill, over low obstacles may help Fido stay flexible, study shows (Source: The Doctors Lounge - Health News)
Certain Exercises Benefit Arthritic Dogs
Walking uphill, over low obstacles may help Fido stay flexible, study shows Source: HealthDay Related MedlinePlus Page: Pet Health (Source: MedlinePlus Health News)
Metacarpophalangeal Joints in Rheumatoid Arthritis: Delayed Gadolinium-enhanced MR Imaging of Cartilage--A Feasibility Study [Musculoskeletal Imaging]
Conclusion: Delayed gadolinium-enhanced MR imaging of cartilage of the MCP joints is feasible at 3.0 T. Delayed gadolinium-enhanced MR imaging of cartilage may help to assess cartilage degeneration in morphologically normal-appearing MCP II and III cartilage in patients with RA. &copy; RSNA, 2010 (Source: Continuous Publishing articles)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
New Insights Into Detecting Osteoarthritis Via Sodium MRI, NYU Researchers Find
Researchers at New York University have developed an innovative way to look at the development of osteoarthritis in the knee joint - one that relies on the examination of sodium ions in cartilage. Their work, which appears in the Journal of Magnetic Resonance, may provide a non-invasive method to diagnose osteoarthritis in its very early stages. The concentration of sodium ions, which are distributed in the body, is known to reveal the location of glycosaminogycans (GAGs) in cartilage tissues... (Source: Health News from Medical News Today)
Health Tip: Snug Shoes Can Damage Feet
Title: Health Tip: Snug Shoes Can Damage FeetCategory: Health NewsCreated: 8/30/2010 10:10:00 AMLast Editorial Review: 8/31/2010 (Source: MedicineNet Arthritis General)
New developments in osteoarthritis. Prevention of injury-related knee osteoarthritis
Purpose of Review: This review presents recent data on knee joint injury as a major cause of osteoarthritis (OA), and promising developments in primary and secondary prevention of OA related to injury. In particular, the role of neuromuscular and biomechanical factors in primary injury prevention and their proposed role in treatment after injury to prevent OA are reviewed and discussed.Recent Findings: Knee OA after injury is common, especially in young adults. There has been an alarming increasing in knee injuries, particularly in females, in the past two decades. Knee OA due to injury estimated at 14-25% a decade ago may be higher now. Convincing level 1 and 2 evidence has shown that the majority of ACL and other injuries are preventable with neuromuscular training programs to improve tr...
New developments in osteoarthritis. Prevention of injury-related knee osteoarthritis: opportunities for the primary and secondary prevention of knee osteoarthritis
Where risk factors have been identified in knee and hip osteoarthritis (OA), with few exceptions, no prevention strategies have proven beneficial. The major risk factors for knee OA are advanced age, injury and obesity. However, there is limited or no evidence that they are modifiable or to what degree modifying them is effective in preventing development of knee OA or in preventing symptoms and progressive disease in persons with early OA. The notable exception is the growing epidemic of (sports) injury related knee OA. This review details the biological and clinical data indicating the efficacy of interventions targeting neuromuscular and biomechanical factors that make this subset of OA an attractive public health target, and highlights research opportunities for the future. (Source: Ar...
Functional CCR5 Receptor Protects Patients With Arthritis From High Synovial Burden of Infecting Chlamydia trachomatis.
CONCLUSION:: These results indicate that the wt/wt genotype is associated with attenuated synovial bacterial load compared with loads in wt/Delta32 patients. Although no alleles other than Delta32 were assessed, our data suggest that this allele provides little/no protection from ReA in patients infected with Chlamydia- but it may provide some protection in patients with UO. The basis of this possible differential effect of CCR5 genotype is under study. PMID: 20811274 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
NHGRI selects new scientific director for intramural research
Daniel L. Kastner, M.D., Ph.D.,has been selected to be the Scientific Director of the National Human Genome Research Institute (NHGRI), NHGRI Director Eric D. Green, M.D., Ph.D., announced. Dr. Kastner currently serves as Clinical Director and Director of Translational Research at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). NHGRI and NIAMS are two of the 27 institutes and centers that make up the National Institutes of Health. Dr. Kastner will assume his position at NHGRI in early October Top of page August 15, 2010: Discovered gene causes Kabuki syndrome Using a new, rapid and less expensive DNA sequencing strategy, scientists have discovered genetic alterations that account for most cases of Kabuki syndrome, a rare disorder that causes multip...
A Step Closer To Development Of Drug To Prevent Deadly Immune Response
Researchers have isolated a molecule, small enough to be used as a drug, that can shut down a dysfunctional immune response that causes deadly hemorrhagic shock, results in delayed death of heart attack patients, promotes rejection of transplanted organs and destroys joints in patients with rheumatoid arthritis, according to a paper published in Molecular Immunology... (Source: Health News from Medical News Today)
Vitamin D really does prevent cancer, autoimmune diseases
(NaturalNews) A new study out of Oxford University pinpoints vitamin D deficiency as a culprit in serious illnesses like cancer and autoimmune disorders. According to the report, which was recently published online in the journal Genome Research, genetic receptors throughout the body need adequate vitamin D levels to prevent these and other serious illnesses from developing.Multiple sclerosis, diabetes, rheumatoid arthritis, Chron's disease, leukemia -- these and many more diseases are often caused by a lack of vitamin D. Your genes literally have receptors that need vitamin D in order to properly express themselves. If there is not enough of the vitamin, serious illness is prone to develop.The Oxford team made specific observations about the importance of vitamin D in the genome regions a...
Bladder Cancer
Title: Bladder CancerCategory: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 8/30/2010 (Source: MedicineNet Arthritis General)
Food Better Than Supplements for Cancer Prevention: Expert
Title: Food Better Than Supplements for Cancer Prevention: ExpertCategory: Health NewsCreated: 8/27/2010 10:10:00 AMLast Editorial Review: 8/30/2010 (Source: MedicineNet Arthritis General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
The complications of high tibial osteotomy: CLOSING- VERSUS OPENING-WEDGE METHODS.
Authors: Song EK, Seon JK, Park SJ, Jeong MS We compared the incidence and severity of complications during and after closing- and opening-wedge high tibial osteotomy used for the treatment of varus arthritis of the knee, and identified the risk factors associated with the development of complications. In total, 104 patients underwent laterally based closing-wedge and 90 medial opening-wedge high tibial osteotomy between January 1993 and December 2006. The characteristics of each group were similar. All the patients were followed up for more than 12 months. We assessed the outcome using the Hospital for Special Surgery knee score, and recorded the complications. Age, gender, obesity (body mass index &gt; 27.5 kg/m(2)), the type of osteotomy (closing versus opening) and the pre-operativ...
Revision interposition arthroplasty of the elbow.
Authors: Larson AN, Adams RA, Morrey BF Between 1996 and 2008, nine patients with severe post-traumatic arthritis underwent revision of a failed interposition arthroplasty of the elbow with a further interposition procedure using an allograft of tendo Achillis at a mean of 5.6 years (0.7 to 13.1) after the initial procedure. There were eight men and one woman with a mean age of 47 years (36 to 56). The mean follow-up was 4.7 years (2 to 8). The mean Mayo Elbow Performance score improved from 49 (15 to 65) pre-operatively to 73 (55 to 95) (p = 0.04). The mean Disability of the Arm, Shoulder and Hand score was 26 (7 to 42). One patient was unavailable for clinical follow-up and one underwent total elbow replacement three months post-operatively. Of the remaining patients, one had an exce...
Septic arthritis or transient synovitis of the hip in children: THE VALUE OF CLINICAL PREDICTION ALGORITHMS.
Authors: Sultan J, Hughes PJ The crucial differentiation between septic arthritis and transient synovitis of the hip in children can be difficult. In 1999, Kocher et al introduced four clinical predictors which were highly predictive (99.6%) of septic arthritis. These included fever (temperature &gt;/= 38.5 degrees C), inability to bear weight, white blood-cell count &gt; 12.0 x 10(9) cells/L and ESR &gt;/= 40 mm/hr; CRP &gt;/= 20 mg/L was later added as a fifth predictor. We retrospectively evaluated these predictors to differentiate septic arthritis from transient synovitis of the hip in children over a four-year period in a primary referral general hospital. When all five were positive, the predicted probability of septic arthritis in this study was only 59.9%, with fever being the ...
Role of extracellular membrane vesicles in the pathogenesis of various diseases, including cancer, renal diseases, atherosclerosis, and arthritis
Authors: H Clarke Anderson, Douglas Mulhall & Rama Garimella (Source: Laboratory Investigation AOP)
Arthritis Impacts African-Americans and Hispanics More than Whites
Arthritis causes more pain and limitations for African-Americans and Hispanics than for whites, according to a study released by the Centers for Disease Control and Prevention. (Source: Disabled World)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Sparboe Farms Initiated Voluntary Recall Fresh Shell Eggs
Sparboe Farms is voluntarily recalling shell eggs produced by Wright County Egg and Hillandale Farms which were packaged by Sparboe Farms, because they have the potential to be contaminated with Salmonella. Salmonella is an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems.Healthy persons infected with Salmonella often experience fever, diarrhea, nausea, vomiting and abdominal pain. In rare circumstances, infection with Salmonella can result in the organism getting into the bloodstream and producing more severe illnesses such as arterial infections, endocarditis, or arthritis. (Source: Food and Drug Administration)
Rheumatoid arthritis drugs approved
A number of new drugs for patients with rheumatoid arthritis have been recommended by NICE. (Source: Nursing Times Breaking News)
Sunlight protects against diabetes and MS
A lack of exposure to sunlight can be a factor in a number of diseases including multiple sclerosis, type-1 diabetes, rheumatoid arthritis and some forms of cancer, a major UK study has concluded. (Source: Nursing Times Breaking News)
Physiotherapy For Arthritic Pets
On receiving an honour, the American entertainer Jack Benny once said, "I don't deserve this award but I have arthritis and I don't deserve that either." Unfortunately, Benny was not alone in suffering from arthritis as he grew older. Arthritis is associated with significant discomfort and simple activities such as going for walks and climbing stairs often become extremely painful. A variety of treatments are available, usually involving a combination of drugs and physiotherapy, but these generally only address the symptoms rather than curing the condition... (Source: Health News from Medical News Today)
Reimbursement of pharmaceuticals: reference pricing versus health technology assessment
This study focussed on decisions about the initial price and reimbursement status of innovative drugs and discussed the consequences for market access and cost. Four countries were studied: Germany, The Netherlands, Sweden and the United Kingdom. These countries have operated one, or both, of the two policies at certain points in time, sometimes in parallel. Drugs in four groups were considered: cholesterol-lowering agents, insulin analogues, biologic drugs for rheumatoid arthritis and ?atypical? drugs for schizophrenia. Compared with HTA, reference pricing is a relatively blunt instrument for obtaining value for money from pharmaceuticals. Thus, its role in making reimbursement decisions should be limited to drugs which are therapeutically equivalent. HTA is a superior strategy ...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
[Juvenile arthritides.]
Authors: Horneff G Arthritis in children represents a diagnostic and therapeutic challenge. The diagnostic spectrum is broad and a very precise indication for diagnostic and therapeutic procedures, especially in small children, is important. In addition to acute arthritides - viral arthritis, reactive arthritis, Lyme arthritis and septic arthritis - secondary chronic arthritis related to an underlying disease as well as juvenile idiopathic arthritis (JIA), the most common chronic inflammatory systemic disease in children, need to be considered. This overview is a guide to the diagnosis of arthritis in childhood and to evidence-based therapy of JIA in particular. This consists of a combination of nonsteroidal anti-inflammatory drugs, systemic and intraarticular corticosteroids, traditio...
Transmission of circulating cell-free AA amyloid oligomers in exosomes vectors via a prion-like mechanism.
Authors: Tasaki M, Ueda M, Ochiai S, Tanabe Y, Murata S, Misumi Y, Su Y, Sun X, Shinriki S, Jono H, Shono M, Obayashi K, Ando Y Recent studies clearly demonstrated that several types of pathogenic amyloid proteins acted as agents that could transmit amyloidosis by means of a prion-like mechanism. Systemic AA amyloidosis is one of the most severe complications of chronic inflammatory disorders, particularly rheumatoid arthritis. It is well known that, similar to an infectious prion protein, amyloid-enhancing factor (AEF) acts as a transmissible agent in AA amyloidosis. However, how AEF transmits AA amyloidosis in vivo remained to be fully elucidated. In the present study, we focused on finding cell-free forms of AEF and its carriers in circulation by using the murine transfer model of A...
CCR5 Antagonist AZD5672 Ineffective in Rheumatoid Arthritis
Despite showing promise in preclinical studies, the CCR5 antagonist AZD5672 was no better than placebo in patients with rheumatoid arthritis, researchers report in the online July 26th Arthritis & Rheumatism. Reuters Health Information (Source: Medscape Rheumatology Headlines)
Orbital Inflammatory Pseudotumors: Etiology, Differential Diagnosis, and Management
Abstract&nbsp;&nbsp;Orbital inflammation is typically an idiopathic process that occasionally may be identified with a specific local or systemic disease as the causative agent. Orbital inflammatory pseudotumor (also known as idiopathic orbital inflammation syndrome, orbital pseudotumor, nonspecific orbital inflammation, and orbital inflammatory syndrome) is defined as an idiopathic tumor-like inflammation consisting of a pleomorphic cellular response and a fibrovascular tissue reaction. Various rheumatologic disorders are associated with orbital inflammation and must be ruled out in cases of orbital inflammatory pseudotumor, including Wegener?s granulomatosis, giant cell arteritis, systemic lupus erythematosus, dermatomyositis, and rheumatoid arthritis. The mainstay of therapy is co...
Gout and coexisting pseudogout in the knee joint
Conclusions&nbsp;&nbsp;Our findings suggest that the coexistence of gout and pseudogout should be considered in the diagnosis of crystal-induced arthritis. Careful crystal evaluation using compensated polarized microscopy may reveal similar cases with MSU and CPPD crystals in the same joint. Content Type Journal ArticleDOI 10.1007/s00167-010-1236-8Authors Yonsik Yoo, Center for Arthroscopy, Department of Orthopaedic Surgery, Hallym University Hangang Sacred Heart Hospital, 94-200 Youngdeungpo-Dong, Youngdeungpo-Ku, 150-719 Seoul, KoreaYoung-Jin Seo, Center for Arthroscopy, Department of Orthopaedic Surgery, Hallym University Hangang Sacred Heart Hospital, 94-200 Youngdeungpo-Dong, Youngdeungpo-Ku, 150-719 Seoul, KoreaMina Huh, Center for Arthroscopy, Department of Orthopaedic ...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Does broccoli aid gut problems?
Conclusion This carefully conducted laboratory study indicates that soluble fibres from certain plant foods can reduce the transport of E coli strains associated with Crohn?s, and their transfer across specialised cells of the bowel lining. It also shows that one emulsifier used in food processing has the opposite effect, by increasing transport. This is early research aimed at furthering our understanding of how dietary and environmental factors might have a role in the development of Crohn?s. However, the findings have no current implications for the prevention or treatment of the disease, and it cannot be concluded from this study alone that any of these substances affect the development of Crohn?s. The study has not shown that eating broccoli or plantain reduces disease activity ...
Rodent of the Week: Can having rheumatoid arthritis protect against Alzheimer's disease?
A protein released when rheumatoid arthritis is present in the body may reduce the risk of Alzheimer's disease. The surprise finding in a mouse study may explain why people with rheumatoid arthritis have lower rates of developing Alzheimer's. Experts... (Source: OrlandoSentinel: Medical Research)
Quality and Coordination of Care for Patients With Multiple Conditions: Results From an International Survey of Patient Experience
This article presents patient-reported experiences of health care among 8,973 of chronically ill adults from eight countries, using telephone survey data. We designed a &lsquo;&lsquo;morbidity score&rsquo;&rsquo; combining the number of conditions and reported health status. Respondents with high morbidity scores reported less favorable experience with coordination of care compared to those with low morbidity scores. They also reported lower ratings of overall quality of care. There were no differences in reported experience with the individual physicians. Comparing type of comorbidity, chronic lung, and mental health problems were associated with lower ratings than hypertension, heart disease, diabetes, arthritis, and cancer. The implications and limitations of this study are discussed in...
Self?management strategies used during flares of rheumatoid arthritis in an ethnically diverse population
(Source: Musculoskeletal Care)
Vascularized Bone Grafting of Scaphoid Nonunions
Scaphoid fractures represent the most common carpal fracture and must always be included in the differential diagnosis for wrist pain in the athlete. In the short-term, nonunions may result in mild discomfort; however, the long-term sequelae of nonunions result in a predictable descent into wrist arthrosis. Athletes with excellent compensatory ability and multiple incentives to continue in sport may neglect these injuries until significant disruption of the scaphoid blood supply or arthritic changes have already occurred. The restoration and evaluation of scaphoid vascularity represent a challenging and important area of hand surgery. Magnetic resonance imaging and computed tomography (CT) scans have important roles in evaluating these injuries before and after surgery. Stable fixation and...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Does Hope Have a Dark Side?
Title: Does Hope Have a Dark Side?Category: Health NewsCreated: 8/26/2010 10:10:00 AMLast Editorial Review: 8/27/2010 (Source: MedicineNet Arthritis General)
Health Tip: When Hip Pain Signals Bursitis
Title: Health Tip: When Hip Pain Signals BursitisCategory: Health NewsCreated: 8/26/2010 10:10:00 AMLast Editorial Review: 8/27/2010 (Source: MedicineNet Arthritis General)
Long-Term Exercise Can Reduce Vets' Muscle Pain
Title: Long-Term Exercise Can Reduce Vets' Muscle PainCategory: Health NewsCreated: 8/26/2010 6:10:00 PMLast Editorial Review: 8/27/2010 (Source: MedicineNet Arthritis General)
Lung Disease Plaintiff Says Learned Intermediary Requires Adequate Warning
CLEVELAND - A drug manufacturer may not assert the learned intermediary as a defense when it has not warned of the injury asserted, a plaintiff who alleges that Remicade caused noninfectious interstitial lung disease (NILS) says in a July 30 brief in Ohio federal court opposing dismissal (Anthony DeGidio v. Centocor, Inc., et al., No. 3:09-cv-721, N.D. Ohio.; See July 2009, Page 10). Full story on lexis.com (Source: LexisNexis&#174; Mealey's&#8482; Arthritis Drugs Legal News)

and buy cheap Generic Viagra (up to 60% cheaper than the branded Viagra). Soaring drug and health insurance costs are pushing more and more people in the US and other countries into buying drugs from foreign pharmacies to save money on their prescription drug costs.

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